Example sentences with "tertile", translation memory
A total of 305 patients were enrolled in the MA.19 trial. Of the 191 patients in whom cancer metastasized or recurred within 36 months from original diagnosis to trial entry, patients in the arm combining doxorubicin with tesmilifene had a median survival of 29.7 months compared to 12.2 months for patients on doxorubicin alone, a 143% improvement in overall survival (p=0.0016). The patient population of 305 was divided into tertiles of patients who had a disease-free interval (DFI) of greater than 36 months, 6 to 36 months and less than 6 months.
Given the small number of exposed individuals in this tertile (n=15) and the wide divergence in estimates between mathematical models, these results should be interpreted with caution but they support the assumption that iron deficiency represents a risk factor for manganese neurotoxicity.
Some industry-based validity studies support this idea.3,57 In the community-based setting, Fritschi et al. found that three experienced expert raters working independently were able to identify 64%, 70% and 80% of past occupational exposures, respectively, across a variety of workplaces.58 As well, in the present study, we observed no statistically significant trends in over- or underreporting across three time periods of expert assessment (PAH exposures were sorted in order of expert assessment and then split into tertiles; trends in percent under- and overreporting were p > 0.05, respectively, in Mantel-Haenzsel chisquare tests for trend), thus providing some evidence of expert consistency over time (data not shown).
The tertile with the steepest slope that was significantly different from the all-data model was reported and assumed to reflect the most sensitive of the groups.
Participants were grouped into physical activity level categories by AEE and physical activity intensity (based on MET values), and physical activity level changes were determined from movement between tertiles of AEE from baseline to follow-up.
Food source Vitamin C (lowest vs highest tertile) Manganese Vitamin A Retinol Beta carotene, vitamin E, zinc and selenium Vitamin E (/10 mg) Beta carotene (/1 mg) Vitamin C (/100 mg) Flavonoids (/10 mg) Vitamins A, B, C, E and beta carotene From supplements:
Some arbitrary reassignments were made where the average earnings of cusp fields were closer to the adjacent grouping than the others in its original tertile.
Thus we classified the fields of study in each cohort by approximate tertiles of post-graduation earnings.
Dichotomous/nominal/ordinal responses were coded as in the original questionnaire, and the few continuous variables were categorized into tertiles.
For ARE, four models with interactive effects were significant, highlighting the enhanced sensitivity of 3 sub-groups of subjects: 1) the oldest tertile (>48 years) of subjects exhibited a significantly larger decrement in SPES finger-tapping due to manganese exposure; 2) subjects in the highest tertile of alcohol consumption (>23.75 g/day) for the Luria Nebraska thumb-fingers test (non-dominant hand); and 3) subjects with more than 20 years of smoking for the Luria Nebraska hand-clench test (non-dominant hand) and the test of NVCST (left eye/1.5 cycles).
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