blue balls in English dictionary blue balls Meanings and definitions of "blue balls" (slang) A cramp-like ache in the testicles and prostate region caused by prolonged sexual arousal. noun (slang) A cramp-like ache in the testicles and prostate region caused by prolonged sexual arousal. noun (figuratively) Unfulfilled sexual desire. more Grammar and declension of blue balls blue balls ( plural only) more Sample sentences with "blue balls" Declension Stem Match words all exact any Try again Available translations German Hungarian Persian Spanish Authors